Eager to flee the parochialism of her French upbringing, and a painful family past, the young and beautiful Marina falls in love with a seductive Greek sea-captain she meets at the port of Rouen. She follows him to the Aegean island of Syros to begin a new life as a married woman in the home of her formidable mother-in-law. Enchanted by the beauty of her surroundings, and fascinated by her husband`s erudite younger brother, she aspires to learn all she can about contemporary Greek culture and live up to the ideals of her classical education. But when disaster upends her husband`s shipping business and the comfortable stability of their life together, Marina`s world slides into a vicious circle of love, passion, and death.

Set in the early decades of the twentieth century, The Great Chimera is an exquisite account of the inner life of the heroine, and the collisions of different cultures and ways of being. In prose that ranges from the lyrical to the tersely realist, Karagatsis weaves a classic tale that is wide-ranging in its literary references, and devastating in its psychological nuance. This modern Greek tragedy has been made into a TV series and a highly acclaimed stage play, enjoying three sold-out seasons in Athens, and an international tour.